Isopropyl myristate is a traditional, fast spreading emollient for modern cosmetic applications. Pdf isopropyl myristate finds many applications in food, cosmetic and pharmaceutical industries as an emollient, thickening agent, or lubricant. Pdf isopropyl myristate production process optimization. Tetradecanoic acid, 1methylethyl ester chemical formula. Isopropyl myristate ipm is the ester of isopropyl alcohol and myristic acid. Isopropyl myristate is defined as a synthetic oil that is popularly used in both the cosmetics industry as well as the pharmaceutical industry. Ipm is used to dissolve lanolin and other oils, and is commonly used as a degreasant or softener in sunscreens, face creams and lipsticks. There is also research showing it can help enhance the absorption of ingredients in a cosmetic formula. Isopropyl myristate is often called out as being a particularly bad poreclogging ingredient. Hallstar ipmnf is a multifunctional emollient, solvent, spreading agent, penetrant synthetically produced ester of isopropyl alcohol and myristic acid that conforms to the requirements of the national formulary monograph for isopropyl myristate. However, a grade of 4 to 5 is uniformally reproduceable and considered positive. This product contains alcohol and is subject to extra fees for air shipping. This thesis starts with a brief overview of the current production processes for fatty acid esters.
Final report on the safety assessment of myristyl myristate and isopropyl myristate acute. Add phase b into phase a under high stirring and maintain during 10 min. Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption. Additionally, it can be used in bath oils, massage oils and perfumes. Avoid runoff into storm sewers and ditches which lead to waterways. Isopropyl myristate, with the chemical formula ch 3 ch 2 12 cooch ch 3 2, is an ester of myristic acid, an essential fatty acid derived from palm kernel oil and isopropyl alcohol. Isopropyl myristate is a synthetic oil used as an emollient, thickening agent, or lubricant in beauty products. Hence it finds broad application in topically applied cosmetic and pharmaceutical liquid, cream, lotion, powder and spray products. The panel did another evaluation in 2002 and came to the same conclusion.
Isopropyl myristate american international chemical inc. Any website that suggests this material is harmful should be ignored. Back in 1986 there was a study published in the archives of dermatology which demonstrated that isopropyl myristate had the propensity to clog pores in the rabbit ear assay hope that did not rile up the norfolk. Isopropyl myristate finds many applications in food, cosmetic and. Isopropyl myristate is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired. Lastly, isopropyl myristate is also believed to have strong skin penetrating properties. Anhydrous nonalcoholic mineral sunscreen spray spf 30 by hallstar this anhydrous nonalcoholic mineral sunscreen spray spf 30 spray provides broad spectrum sun protection. Isopropyl myristate, the ester of myristic acid and isopropyl alcohol, is also used in topical medications. Isopropyl myristate emmoliant that promotes skin absorption for skin conditioners tocopheryl acetate vitamin e for skincare acrylatesc1030 alkyl acrylate crosspolymer is a synthetic ingredient used as a thickening agent, texture enhancer, filmforming agent, and emulsifier in cosmetics and personal care products.
Green synthesis of isopropyl myristate in novel single phase. Presented at the southern california section, california chapter, society of cosmetic chemists, spring 1989. Isopropyl myristate is being studied as a skin enhancer. It is also recommended for use in cosmetic products such as hair spray, hair. As reported in our previous studies, a minimal grade of 0 to 1 is not considered significant. There are no methods described for the analysis of ipts in cosmetic products. Pediculicide widespread and common in children between the ages of 3 and 12. It is being increasingly used in the cosmetic industry because of its excellent emollient and solvent properties. Ester of isopropyl alcohol and myristic acid vegetablederived. Pdf green synthesis of isopropyl myristate in novel single phase. Isopropyl myristate is a clear, yellowishbrown liquid with isoprkpyl faint sweet odor. Apr 19, 2017 isopropyl myristate is defined as a synthetic oil that is popularly used in both the cosmetics industry as well as the pharmaceutical industry. Chemical product and company identification product name. Mar 05, 2020 isopropyl myristate emmoliant that promotes skin absorption for skin conditioners tocopheryl acetate vitamin e for skincare acrylatesc1030 alkyl acrylate crosspolymer is a synthetic ingredient used as a thickening agent, texture enhancer, filmforming agent, and emulsifier in cosmetics and personal care products.
It is also used as a flavoring agent in the food industry. Isopropyl myristate, food and flavor ingredient, flavis no. This is a valuable attribute, as isopropyl myristate can help other skin healing chemicals to penetrate more deeply. Isopropyl myristate was minimally irritating to the rabbits eyes and was not a skin sensitizer in studies with guinea pigs. Final report of the amended safety assessment of myristic acid and. Isopropyl myristate is known as a penetration enhancer for topical preparations. Microorganisms capable of utilizing the ingredient for growth included 12 of 23 strains bacteria. This cosmetic ingredient produced minimal to mild skin irritation, minimal eye irritation in. Use of dibutyl adipate and isopropyl myristate in topical and. Comedogenicity and irritancy of commonly used ingredients in skin care products james e. Sample recipe for isopropyl myristate making cosmetics. Isopropyl myristate dewolf chemical an azelis company. In limited studies, isopropyl myristate was not carcinogenic on the skin of mice, but a mixture of. Its used in cosmetic and topical medicinal preparations.
Isopropyl myristate is also a great, nontoxic solvent for monster clay. Hallstar ipmnf is nonocclusive, spreads well, and provides an elegant, nonoily skin feel. Final report on the safety assessment of myristyl myristate. Further research may identify additional product or industrial usages of this chemical. Isopropyl myristate is an ingredient found in a number of cosmetic formulations. Committee to evaluate drugs ced isopropyl myristate. Its also perfect as a perfume diluent in place of other oils or alcohol.
In lotions, creates a nice slip and helps it absorb quickly on the skin. Isopropyl myristate isopropyl myristate 3 brenntag neolone ph 100 phenoxyethanol 0,9 dowchemical c dissolvine gl47s tetrasodium glutamatediacetate 0,3 akzo nobel cerise tbc fragrance 0,3 givaudan procedure 1. Isopropyl myristate is perfectly safe as a cosmetic ingredient and there are no issues with it as far as end users are concerned. Isopropyl myristate ipm is used as a makeupglue remover for prosthetics or as an ingredient in makeup products.
Final report on the safety assessment of myristyl myristate and. Cosmetic is a greek word which means to a dorn addition of something decorative to a. Isopropyl myristate can be used to dilute aroma chemicals. Acute oral and dermal toxicity tests indicated that myristyl myristate is nontoxic to rats. Apr 27, 2020 isopropyl myristate more suppliers company name meryer shanghai chemical technology co. Comedogenicity and irritancy of commonly used ingredients in. Patient information sheet isopropyl myristate i003 your patch testing results indicate that you have a contact allergy to isopropyl. Effectiveness of isopropyl myristatecyclomethicone d5.
Isopropyl myristate is a synthetic oil widely used in the cos. Gentle oilbased makeup remover which removes many types of makeup including pax prosaide and grease makeups. Readily adsorbed by the skin when used at high concentrations it gently lifts makeup and surface dirt. Jun 08, 2011 isopropyl myristate is perfectly safe as a cosmetic ingredient and there are no issues with it as far as end users are concerned. In cosmetics and personal care products, isopropyl myristate functions as a binder, and skinconditioning agent a emollient. Amended safety assessment of alkyl esters as used in. Food and drug administration cosmetic labeling guide. It is widely used as a nontoxic alternative for the control of head lice, as an emollient, and a lubricant. Because these processes have several drawbacks, a new technology is proposed. Low viscosity fluid nongreasy emollient, tolerates wide ph range, compatible with most surfactants. Packaging 1 kg in poly bottle 8, 20 kg in poly drum biochemphysiol actions odor at 1. Further, nothing contained herein shall be taken as any inducement or recommendation to use, manufacture or sell that may infringe any patents or any other proprietary rights now or.
Comedogenicity and irritancy of commonly used ingredients. It has been attacked by scaremongers either from ignorance or more likely from a cynical desire to sell inferior products at high prices. Making cosmetics inc shipped it quickly and i am happy to be able to have access to it so easily. Find msds or sds, a coa, data sheets and more information. Examples of some of the highest concentrations of spray uses are up to 76.
Final report on the safety assessment of myristyl myristate and isopropyl myristate acute oral and dermal toxicity tests indicated that myristyl myristate is nontoxic to rats. Products containing the myristates are applied to all areas of the skin, hair, nails, and mucous. Isopropyl myristate ipm makeup and adhesive remover stage. Isopropyl myristate azelis uk life sciences isopropyl myristate charkit chemical company, llc. Amended safety assessment of alkyl esters as used in cosmetics. Isopropyl myristate is a unique ingredient, and is used in a variety of cosmetic products.
Isopropyl myristate resultz 50% topical solution class of drugs. We search the world and bring only the highest quality materials to customers throughout australia, new zealand, malaysia and the united states of america. Redox is a leading distributor of chemicals and ingredients, active in more than 1,000 specialty and commercial products. Isopropyl myristate is used in a wide range of cosmetic and skincare products as a conditioning agent. Myristyl myristate was included in cosmetic products at concentra tions up to 25%. This chemical is an emollient used in cosmetic and pharmaceutical bases. Committee to evaluate drugs ced recommendations and reasons this document posted april 2010 isopropyl myristate product. In cosmetic manufacturing this ingredient is used to give the finished product a slicker, smoother feel rather than an oily one inci name. Isopropyl myristate was listed in all concentration ranges.
It is a clear, colorless, almost odorless oil of medium polarity with a mean molecular weight, and a spreading value of approx. This chemical can be identified by different names, including. Pdf textbook of cosmetic formulations researchgate. Ipm, the isopropyl ester of myristic acid, is used in cosmetics as a substitute for natural oils. Reactive distillation for cosmetic ingredients an alternative for the production of isopropyl myristate. It can also be used at 100% as a perfume base, like in this recipe. Isopropyl myristate more suppliers company name meryer shanghai chemical technology co. Composed of of isopropyl alcohol a propane derivative and myristic acid a naturallyoccurring fatty acid, isopropyl myristate is a popular cosmetic and pharmaceutical ingredient. Sigmaaldrich offers a number of isopropyl myristate products. Isopropyl myristate is mainly used as a solubilizer, emulsifier and emollient in cosmetic and topical medicines. Additionally, some of the alkyl esters are used in cosmetic sprays and could possibly be inhaled.
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